IgG (7 S Gamma Globulin) Metabolism in Hypogammaglobulinemia: Studies in Patients with Defective Gamma Globulin Synthesis, Gastrointestinal Protein Loss, or Both*

Human Gamma Globulin.

Gamma globulin prophylaxis.

THE importance of infectious hepatitis as a world-wide problem has been highlighted in detail during the presentations made at this symposium. It is clear that as of today (May I 8, I968) there is no published report confirming the isolation of infectious hepatitis virus in a tissue-culture system or animal host. Experience with poliomyelitis, measles, and rubella has revealed that the time int...

Gamma Globulin Metabolism in Rabbits during the Anamnestic Response

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globul...

Gamma Globulin Turnover and Intestinal Degradation of Gamma Globulin in the Dog.

Increased catabolism of plasma proteins by leakage into the gastrointestinal tract and subsequent digestion by the intestinal enzymes are frequently the causes of hypoproteinemia (1-5). The presence of plasma proteins has been demonstrated both in saliva and in the gastric and intestinal juice of normal individuals; therefore, gastrointestinal leakage of plasma proteins may account for a substa...

Disturbances in gamma globulin synthesis as experiments of nature.

Aicle(l lw grants frommi the IICICI1 I lay \Vlmitmiev Foundation, U. S. Public Health Service, American 1 leart Association, ‘sIinnesota I Icart Association, the \Iinnesota I)ivision of the Amucl ican Camicer Society, and the University of Minnesota Graduate Research Fund. Presented in part at the Annual Meeting, October 5, 1955. ADDRESS: (RAG.) Variety Climb heart I lospital, slirmneapolis 14,...